Description

3-Bromo-1,1,1-Trifluoroacetone Oxime is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl groups, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Acts as a precursor for specialty monomers or ligands used in the development of advanced polymers and catalysts.
• Fluorine Chemistry: A valuable reagent for introducing the -CF3 moiety into organic frameworks via further functionalization of the oxime or bromine groups.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed coupling reactions (e.g., Suzuki, Heck) to create more complex molecular architectures.

Basic Information

Product Name	3-Bromo-1,1,1-Trifluoroacetone Oxime
CAS No.	117341-57-8
Molecular Formula	C3H3BrF3NO
Molecular Weight	197.96 g/mol
Synonyms	1,1,1-Trifluoro-3-bromoacetone oxime; 3-Bromo-1,1,1-trifluoroacetoxime; 3-Bromo-1,1,1-trifluoro-2-propanone oxime; 3-Bromotrifluoroacetone oxime; (Z)-3-Bromo-1,1,1-trifluoroacetone oxime; (E)-3-Bromo-1,1,1-trifluoroacetone oxime; Bromotrifluoroacetone oxime; BTFA oxime
EINECS	Contact for details

Quality Control

Our 3-Bromo-1,1,1-Trifluoroacetone Oxime is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP requirements for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.