Description

2-Iodobenzylzinc Bromide 0.5M In Thf is a versatile organozinc reagent, specifically a benzylzinc halide, supplied as a standardized 0.5M solution in tetrahydrofuran (THF). This product is a critical building block for the efficient formation of carbon-carbon bonds, particularly in cross-coupling reactions, enabling the synthesis of complex organic molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the preparation of novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for Negishi cross-coupling reactions to introduce the 2-iodobenzyl moiety into drug candidate molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides by constructing complex aromatic and heteroaromatic scaffolds.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, through controlled polymerization or functionalization.
• Fine Chemical Manufacturing: Facilitates the production of high-value, customized aromatic compounds for various specialty chemical applications.
• Academic & Discovery Chemistry: An essential tool for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-Iodobenzylzinc Bromide 0.5M In Thf
CAS No.	117269-71-3
Molecular Formula	C7H6BrIZn
Molecular Weight	368.33 g/mol
Synonyms	(2-Iodobenzyl)zinc bromide; Zinc, bromo(2-iodophenyl)methyl-; Bromo(2-iodobenzyl)zinc; 2-Iodobenzylzinc bromide solution; (2-Iodophenylmethyl)zinc bromide; Benzene, 1-(bromozinciomethyl)-2-iodo-; THF solution of 2-Iodobenzylzinc bromide
EINECS	Contact for details

Quality Control

Every batch of our 2-Iodobenzylzinc Bromide 0.5M In Thf is manufactured and analyzed under strict quality protocols to ensure consistency and reliability for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration, purity, and solvent quality. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C (refrigerated) to maintain stability and prevent decomposition. The solution is highly volatile (THF solvent) and easily oxidized; ensure containers are sealed and handled in a well-ventilated area. For long-term storage, keep under refrigeration and monitor pressure.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	0.5 M in THF
Assay (Titration)	≥ 95% (as C7H6BrIZn)
THF Content	Balance
Water Content (KF)	≤ 0.05%
Identification (NMR/IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.