Description

4-Hydroxyphenyl Chloromethanesulfonate is a specialized organic sulfonate ester compound with significant utility as a key synthetic intermediate. Its value lies in its bifunctional reactivity, featuring both a phenolic hydroxyl group and a reactive chloromethanesulfonate moiety, enabling precise chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors, where it is used to introduce sulfonate ester groups or as a building block for more complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators where the chloromethanesulfonate group acts as a reactive handle.
• Polymer Modification: Employed to functionalize polymers and resins, imparting specific properties like enhanced solubility or reactivity for advanced material applications.
• Cross-linking Agent: Acts as a cross-linker in the production of specialty coatings, adhesives, and thermoset materials.
• Bioconjugation Chemistry: Utilized in biochemical research for labeling or modifying biomolecules such as proteins and peptides.
• Organic Synthesis Building Block: Provides a versatile platform for constructing complex organic molecules in academic and industrial research laboratories.

Basic Information

Product Name	4-Hydroxyphenyl Chloromethanesulfonate
CAS No.	117224-69-8
Molecular Formula	C7H7ClO4S
Molecular Weight	222.65 g/mol
Synonyms	p-Hydroxyphenyl chloromethanesulfonate; 4-Hydroxybenzenol chloromethanesulfonate; Chloromethyl 4-hydroxyphenyl sulfonate; Phenol, 4-, chloromethanesulfonate; (4-Hydroxyphenyl) chloromethanesulfonate; Chloromethanesulfonic acid 4-hydroxyphenyl ester; p-Hydroxybenzyl chlorosulfonate (common name variant)
EINECS	Contact for details

Quality Control

Our production of 4-Hydroxyphenyl Chloromethanesulfonate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (IR, NMR) for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.