Description

6-Oxabicyclo[3.1.0]Hexane-3-Carboxamide,n-Ethyl-,(1Alpha,3Alpha,5Alpha)-(9Ci) is a specialized bicyclic organic compound featuring a unique oxabicyclo[3.1.0]hexane scaffold, which is of significant interest in advanced synthetic chemistry and pharmaceutical research. This high-purity intermediate is valued for its rigid, three-dimensional structure, making it a critical building block for developing novel active pharmaceutical ingredients (APIs) and complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Medicinal Chemistry: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the metabolic stability and bioavailability of drug candidates.
• Asymmetric Synthesis: Employed as a building block in stereoselective synthesis due to its defined (1α,3α,5α) stereochemistry.
• Agrochemical Research: Utilized in the development of novel herbicides or pesticides where the oxabicyclo structure may confer specific biological activity.
• Fine Chemical Synthesis: Acts as a precursor for synthesizing more complex, high-value specialty chemicals and ligands for catalysis.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Oxabicyclo[3.1.0]Hexane-3-Carboxamide,n-Ethyl-,(1Alpha,3Alpha,5Alpha)-(9Ci)
CAS No.	116856-40-7
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	N-Ethyl-6-oxabicyclo[3.1.0]hexane-3-carboxamide; (1α,3α,5α)-N-Ethyl-6-oxabicyclo[3.1.0]hexane-3-carboxamide; 6-Oxabicyclo[3.1.0]hexane-3-carboxamide, N-ethyl-, (1α,3α,5α)-; Ethyl 6-oxabicyclo[3.1.0]hexane-3-carboxamide; Bicyclic oxa-hexane carboxamide derivative; 116856-40-7; (1alpha,3alpha,5alpha)-N-Ethyl-6-oxabicyclo[3.1.0]hexane-3-carboxamide
EINECS	Contact for details

Quality Control

Our 6-Oxabicyclo[3.1.0]Hexane-3-Carboxamide,n-Ethyl-,(1Alpha,3Alpha,5Alpha)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.