Description

trans-1,3-Cyclohexanedicarboxylic Acid is a high-purity, versatile alicyclic dicarboxylic acid building block essential for advanced organic synthesis. Its rigid, trans-configured cyclohexane ring provides a unique spatial geometry that is critical for developing molecules with specific stereochemical and physical properties. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to create novel active ingredients, chiral ligands, and high-performance materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its structural rigidity enhances biological activity and environmental stability.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent in the manufacture of polyesters, polyamides, and epoxy resins, improving thermal stability and mechanical strength.
• Ligand & Catalyst Development: Employed in the design of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical & Flavor/Fragrance Intermediate: A building block for complex molecules used in high-value aroma chemicals and specialty fine chemicals.
• Academic & Industrial R&D: A valuable reagent for chemical research in medicinal chemistry, materials science, and synthetic methodology development.

Basic Information

Product Name	trans-1,3-Cyclohexanedicarboxylic Acid
CAS No.	116724-13-1
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(1r,3r)-1,3-Cyclohexanedicarboxylic Acid; trans-Hexahydroisophthalic Acid; (1R,3R)-Cyclohexane-1,3-dicarboxylic Acid; trans-Cyclohexane-1,3-dicarboxylic Acid; 1,3-CHDA (trans); (R,R)-1,3-Cyclohexanedicarboxylic Acid; Cyclohexane-1,3-dicarboxylic acid, trans-; 1,3-Cyclohexanedicarboxylic acid, (1R,3R)-
EINECS	Contact for details

Quality Control

Our trans-1,3-Cyclohexanedicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring stringent standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (trans)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.