Description

(S)-5-Methoxy-2,3-Dihydro-3α-(8-Hydroxy-2,2-Dimethyl-2H-1-Benzopyran-6-Yl)-7-Hydroxy-4H-1-Benzopyran-4-One is a high-purity, chiral benzopyran derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated pharmaceutical intermediate and a key building block for research into bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Natural Product Analog Synthesis: Used to create synthetic analogs of naturally occurring benzopyran-based compounds for biological evaluation.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with specific modes of action.

Basic Information

Item	Details
Product Name	(S)-5-Methoxy-2,3-Dihydro-3α-(8-Hydroxy-2,2-Dimethyl-2H-1-Benzopyran-6-Yl)-7-Hydroxy-4H-1-Benzopyran-4-One
CAS No.	116709-69-4
Molecular Formula	C22H22O6
Molecular Weight	382.41 g/mol
Synonyms	(S)-5-Methoxy-2,3-dihydro-3α-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-7-hydroxy-4H-1-benzopyran-4-one; (3S)-5-Methoxy-2,3-dihydro-3-(8-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-7-hydroxy-4H-chromen-4-one; (S)-Flavanone derivative; (S)-Benzopyranone; CAS 116709-69-4; (S)-enantiomer of a dihydroxy-methoxy benzopyranone; (3S)-3-(8-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-5-methoxy-7-hydroxy-2,3-dihydro-4H-chromen-4-one
EINECS	Contact for details

Quality Control

Our (S)-5-Methoxy-2,3-Dihydro-3α-(8-Hydroxy-2,2-Dimethyl-2H-1-Benzopyran-6-Yl)-7-Hydroxy-4H-1-Benzopyran-4-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.