Description

3-(Methoxycarbonyl)Cyclobutanecarboxylicacid is a versatile cyclobutane derivative featuring both a carboxylic acid and a methyl ester functional group, making it a valuable bifunctional building block in organic synthesis. This compound is prized for its rigid, strained four-membered ring structure, which is instrumental in constructing complex molecular architectures with specific spatial orientations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel active pharmaceutical ingredients (APIs), particularly those requiring constrained, bioactive ring systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclobutane core can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored thermal or mechanical properties.
• Chemical Biology Probes: Useful for creating molecular probes and tags due to its derivatizable functional groups.
• Academic & Industrial R&D: A fundamental building block in exploratory organic chemistry for method development and library synthesis.

Basic Information

Product Name	3-(Methoxycarbonyl)Cyclobutanecarboxylicacid
CAS No.	116569-00-7
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	Cyclobutane-1-carboxylic acid, 3-(methoxycarbonyl)-; Methyl 3-carboxycyclobutanecarboxylate; 3-Carbomethoxycyclobutanecarboxylic acid; 1-Carboxy-3-(methoxycarbonyl)cyclobutane; 3-(Methoxycarbonyl)cyclobutane-1-carboxylic acid; 3-Methoxycarbonylcyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(Methoxycarbonyl)Cyclobutanecarboxylicacid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.