Description

trans-Tetrahydro-2,6-Dimethyl-2H-Pyran-2-Methanol is a specialized chiral building block and intermediate of significant interest in fine chemical synthesis. Its value lies in its unique bicyclic structure, which serves as a versatile scaffold for constructing complex molecules with defined stereochemistry. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring specific stereocenters.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its structural motif can contribute to biological activity.
• Flavor and Fragrance Ingredient: Serves as a precursor for musk-like odorants and other complex aroma chemicals due to its tetrahydro-pyran backbone.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing natural product analogs and novel heterocyclic compounds.
• Ligand and Catalyst Development: Its alcohol functionality and stereochemistry make it a candidate for developing chiral ligands in asymmetric catalysis.

Basic Information

Product Name	trans-Tetrahydro-2,6-Dimethyl-2H-Pyran-2-Methanol
CAS No.	116409-38-2
Molecular Formula	C8H16O2
Molecular Weight	144.21 g/mol
Synonyms	2,6-Dimethyl-5,6-dihydro-2H-pyran-2-methanol, trans-; (2R,6R)-rel-2,6-Dimethyl-5,6-dihydro-2H-pyran-2-methanol; 2-(Hydroxymethyl)-2,6-dimethyl-3,4-dihydro-2H-pyran; Tetrahydro-2,6-dimethyl-2H-pyran-2-methanol; Dihydro-2,6-dimethyl-2H-pyran-2-methanol; A chiral dihydropyran methanol derivative.
EINECS	Contact for details

Quality Control

Our trans-Tetrahydro-2,6-Dimethyl-2H-Pyran-2-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.