Description

((E)-3-Chloro-1-Methylpropenyl)Trimethylsilane is a high-purity organosilicon building block featuring a reactive chloroalkene moiety protected by a trimethylsilyl group. This compound is valued for its role as a versatile synthetic intermediate in advanced organic and organometallic chemistry, enabling precise carbon-carbon and carbon-heteroatom bond formation. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized alkene segments.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific chlorinated alkene structures.
• Organometallic & Cross-Coupling Reagents: Serves as a precursor for generating specialized organometallic reagents used in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki, Stille).
• Polymer & Material Science: Employed in the synthesis of functional monomers and silane-modified polymers for specialty coatings and advanced materials.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing complex, high-value organic molecules.
• Research & Development: A valuable tool in academic and industrial R&D for methodology development and exploring new chemical spaces.

Basic Information

Product Name	((E)-3-Chloro-1-Methylpropenyl)Trimethylsilane
CAS No.	116399-78-1
Molecular Formula	C7H15ClSi
Molecular Weight	162.73 g/mol
Synonyms	(E)-1-Chloro-3-(trimethylsilyl)-2-butene; 3-Chloro-1-methyl-1-(trimethylsilyl)prop-1-ene; 1-Chloro-3-trimethylsilyl-2-butene; (E)-3-Chloro-1-methyl-1-(trimethylsilyl)propene; Trimethyl[(1E)-3-chloro-1-methyl-1-propen-1-yl]silane; (E)-3-Chloro-1-methylprop-1-en-1-yltrimethylsilane
EINECS	Contact for details

Quality Control

Our ((E)-3-Chloro-1-Methylpropenyl)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Purity (E-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.