Description

9,17-Dihydroxy-17-Ethynylandrost-4-En-3-One is a high-purity synthetic steroid derivative with a unique ethynyl modification at the 17-position. This compound is valued as a critical pharmaceutical intermediate and research chemical for the development of novel therapeutic agents. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors for advanced steroid synthesis and biochemical research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in metabolic pathway studies and receptor binding assays.
• Hormone Analog Development: Serves as a precursor for creating modified androgens and other hormone analogs with targeted biological activity.
• Academic & Contract Research: Employed in university and CRO laboratories for investigating steroid chemistry and pharmacology.
• Process Development: Utilized in process chemistry for scaling up and optimizing synthetic routes to complex steroid molecules.

Basic Information

Product Name	9,17-Dihydroxy-17-Ethynylandrost-4-En-3-One
CAS No.	116299-92-4
Molecular Formula	C₂₁H₂₈O₃
Molecular Weight	328.45 g/mol
Synonyms	17α-Ethynyl-4-androstene-3β,17β-diol; 17β-Hydroxy-17α-ethynyl-4-androsten-3-one; 17-Ethynyltestosterone derivative; 9,17-Dihydroxy-17-ethynyl-androst-4-en-3-one; 17α-Ethynyl-3β,17β-dihydroxyandrost-4-ene; Androst-4-ene-3,17-diol, 17-ethynyl-; 116299-92-4; 17-Ethynyl-4-androstene-3β,17β-diol
EINECS	Contact for details

Quality Control

Our 9,17-Dihydroxy-17-Ethynylandrost-4-En-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. Certificates of Analysis (COA) documenting full compliance with agreed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.