Description

(S)-1-Benzyl-3-[(p-Tolylsulfonyl)Oxy]Pyrrolidine CAS NO 116183-79-0 is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in providing a stereochemically defined pyrrolidine scaffold, which is crucial for constructing complex molecules with specific biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, especially those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex, enantiomerically pure molecules in medicinal chemistry.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides with specific modes of action.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Academic & R&D: Fundamental reagent for methodological studies in organic chemistry and process development.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	(S)-1-Benzyl-3-[(p-Tolylsulfonyl)Oxy]Pyrrolidine
CAS No.	116183-79-0
Molecular Formula	C18H21NO3S
Molecular Weight	331.43 g/mol
Synonyms	(S)-1-Benzyl-3-(tosyloxy)pyrrolidine; (S)-1-Benzyl-3-[(4-methylphenyl)sulfonyl]oxy]pyrrolidine; (S)-3-[(p-Toluenesulfonyl)oxy]-1-benzylpyrrolidine; (S)-1-Benzyl-3-(p-toluenesulfonyloxy)pyrrolidine; (S)-N-Benzyl-3-(tosyloxy)pyrrolidine; 1-Benzyl-3-[(p-tolylsulfonyl)oxy]pyrrolidine, (S)-; Pyrrolidine, 1-benzyl-3-[(4-methylphenyl)sulfonyl]oxy]-, (3S)-
EINECS	Contact for details

Quality Control

Our (S)-1-Benzyl-3-[(p-Tolylsulfonyl)Oxy]Pyrrolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.