Description

4-Chloro-2-Methyl-Tetrahydro-Pyran is a versatile chlorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for the creation of novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Chemistry: Employed in the synthesis of complex odorants and flavoring agents due to its pyran-based structure.
• Material Science Research: Investigated as a monomer or building block for specialty polymers and functional materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	4-Chloro-2-Methyl-Tetrahydro-Pyran
CAS No.	116131-46-5
Molecular Formula	C6H11ClO
Molecular Weight	134.60 g/mol
Synonyms	4-Chloro-2-methyloxane; 2-Methyl-4-chlorotetrahydropyran; 4-Chloro-2-methyltetrahydropyran; Tetrahydro-4-chloro-2-methyl-2H-pyran; 2H-Pyran, tetrahydro-4-chloro-2-methyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-Tetrahydro-Pyran is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.