Description

1-Coprosten-3-One Semicarbazone CAS NO 116027-95-3 is a high-purity, chemically defined derivative of a prostaglandin analog, serving as a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its precise chemical structure, which enables the development of targeted therapeutic agents with specific biological activity. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of prostaglandin-based drugs, including those for ocular, cardiovascular, and reproductive health applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of prostaglandin analogs and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or a precursor in studies investigating prostaglandin receptor binding, metabolism, and signaling pathways.
• Ophthalmic Drug Development: Employed in the research and production of prostaglandin-based medications for treating glaucoma and ocular hypertension.
• Veterinary Pharmaceuticals: Utilized in the formulation of drugs for animal health, particularly in reproductive management.
• Process Development & Scale-up: Serves as a critical material for optimizing synthetic routes and scaling production from laboratory to commercial batch sizes.

Basic Information

Product Name	1-Coprosten-3-One Semicarbazone
CAS No.	116027-95-3
Molecular Formula	C23H38N3O3
Molecular Weight	404.57 g/mol
Synonyms	1-Coprosten-3-one, semicarbazone; 17-Phenyl-18,19,20-trinorprostaglandin F2α 1,11-lactone semicarbazone; Cloprostenol Impurity Semicarbazone; (5Z)-9α,11α,15α-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-dien-1-oic acid γ-lactone semicarbazone; PGF2α analog semicarbazone; Prostaglandin F2α derivative semicarbazone
EINECS	Contact for details

Quality Control

Our 1-Coprosten-3-One Semicarbazone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.