Description

2,6-Dichloro-n-Trimethylsilylaniline is a specialized organosilicon compound featuring both halogen and silyl protecting groups on an aniline core. This unique structure makes it a valuable advanced intermediate in organic synthesis, particularly for the development of complex molecules where selective reactivity and steric protection are required. It is primarily utilized by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by fine chemical manufacturers producing high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated aniline structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel organometallic complexes and catalytic systems for asymmetric synthesis.
• Protecting Group Strategy: The trimethylsilyl (TMS) group acts as a protective moiety for the amine functionality in multi-step synthetic sequences.
• Fine Chemical Manufacturing: An essential intermediate for producing custom and high-purity specialty chemicals for research and industrial applications.

Basic Information

Product Name	2,6-Dichloro-n-Trimethylsilylaniline
CAS No.	115910-92-4
Molecular Formula	C9H13Cl2NSi
Molecular Weight	234.20 g/mol
Synonyms	N-(Trimethylsilyl)-2,6-dichloroaniline; 2,6-Dichloro-N-(trimethylsilyl)aniline; 2,6-Dichloro-N-trimethylsilylaniline; Benzenamine, 2,6-dichloro-N-(trimethylsilyl)-; Aniline, 2,6-dichloro-N-(trimethylsilyl)-; 2,6-Dichloro-N-(trimethylsilyl)benzenamine; TMS-2,6-dichloroaniline
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-n-Trimethylsilylaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-aligned environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.