Description

4-Bromo-2-Chloro-5-(Trifluoromethoxy)Aniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromo, chloro, and trifluoromethoxy substituents, provides exceptional reactivity and enables the introduction of specific functional groups into complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Dye Intermediate: Employed in the production of specialty polymers, high-performance resins, and complex organic dyes and pigments.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl and complex heterocyclic systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry, material science, and synthetic methodology development.

Basic Information

Product Name	4-Bromo-2-Chloro-5-(Trifluoromethoxy)Aniline
CAS No.	115844-00-3
Molecular Formula	C7H4BrClF3NO
Molecular Weight	290.47 g/mol
Synonyms	2-Chloro-4-bromo-5-(trifluoromethoxy)aniline; 5-Amino-2-bromo-4-chloro-1-(trifluoromethoxy)benzene; Benzenamine, 4-bromo-2-chloro-5-(trifluoromethoxy)-; 4-Bromo-2-chloro-5-(trifluoromethoxy)benzenamine; 2-Chloro-4-bromo-5-aminotrifluoromethoxybenzene; 4-Bromo-2-chloro-α,α,α-trifluoro-m-anisidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-(Trifluoromethoxy)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.