Description

Guanidine 1,5-Diazabicyclo(5.4.0)Undecane is a highly functionalized bicyclic guanidine base, recognized for its exceptional strength and low nucleophilicity. This compound is a critical reagent in organic synthesis, particularly valued for its role in facilitating challenging deprotonation and condensation reactions under mild conditions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require a powerful, non-nucleophilic base to drive high-yield syntheses.

Application

• As a powerful, non-nucleophilic organic base in deprotonation reactions for the synthesis of sensitive carbanions.
• Catalyst and reagent in pharmaceutical intermediate synthesis, particularly for active pharmaceutical ingredients (APIs).
• Facilitator for condensation and cyclization reactions in heterocyclic chemistry.
• Use in polymerization catalysts and as an initiator for ring-opening polymerizations.
• Reagent in agrochemical synthesis for producing herbicides and fungicides.
• Application in material science for the surface modification of polymers and nanoparticles.
• Utility in asymmetric synthesis when used in conjunction with chiral auxiliaries or ligands.

Basic Information

Product Name	Guanidine 1,5-Diazabicyclo(5.4.0)Undecane
CAS No.	115839-50-4
Molecular Formula	C9H17N3
Molecular Weight	167.25 g/mol
Synonyms	1,5-Diazabicyclo[5.4.0]undec-5-ene; DBU; 2,3,4,6,7,8,9,10-Octahydropyrimido[1,2-a]azepine; Guanidine, cyclic; 8-Azabicyclo[5.4.0]undec-7-ene (common misnomer); DBU base; Diazabicycloundecene; Contact for EINECS details.

Quality Control

Our Guanidine 1,5-Diazabicyclo(5.4.0)Undecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.