Description

2-Fluoro-1-Methylpyridinium Fractogel is a specialized, high-purity chemical reagent designed for advanced synthesis and purification processes. This compound is valued for its role as a versatile alkylating agent and its utility in solid-phase synthesis, particularly in the preparation of complex molecules. It is an essential material for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on nucleoside chemistry, peptide synthesis, and the development of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Oligonucleotide Synthesis: Used as a key reagent for the phosphorylation and activation steps in the automated synthesis of DNA and RNA fragments.
• Pharmaceutical Intermediate Manufacturing: Serves as a critical building block in the synthesis of novel antiviral and anticancer drug candidates.
• Peptide Chemistry: Employed in the preparation of peptide nucleic acids (PNAs) and for modifying amino acid side chains during peptide synthesis.
• Material Science Research: Utilized in the surface functionalization of polymers and gels for chromatography and diagnostic applications.
• Agrochemical Development: Acts as an intermediate in the research and production of advanced, targeted pesticides and herbicides.
• Bioconjugation: Facilitates the labeling and cross-linking of biomolecules for diagnostic and therapeutic purposes.

Basic Information

Product Name	2-Fluoro-1-Methylpyridinium Fractogel
CAS No.	115773-65-4
Molecular Formula	C7H9FN+ (Counterion varies)
Molecular Weight	Contact for details
Synonyms	1-Methyl-2-fluoropyridinium Fractogel; 2-Fluoro-1-methylpyridinium salt; Fractogel-supported 2-fluoro-1-methylpyridinium reagent; 2-Fluoro-N-methylpyridinium polymer-bound; FMP Fractogel; Polymer-bound 2-fluoro-1-methylpyridinium triflate; Solid-supported Mukaiyama's reagent; 2-Fluoro-1-methylpyridinium trifluoromethanesulfonate on Fractogel
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1-Methylpyridinium Fractogel is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and functional performance. Certificates of Analysis (COA) detailing lot-specific results are provided with every shipment to guarantee traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to beige solid beads
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95% (as functionalized polymer)
Loading Capacity	0.5 - 2.0 mmol/g (typical)
Particle Size	Contact for details
Solvent Content	≤ 5% (by Karl Fischer titration)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.