Description

4-Carboxy-3-Chloroacetophenone is a versatile and high-purity aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a carboxylic acid and a chloroacetyl group, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging its reactive halogen and carbonyl functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals requiring specific aromatic substitution patterns.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and condensation reactions.

Basic Information

Product Name	4-Carboxy-3-Chloroacetophenone
CAS No.	115382-35-9
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	3'-Chloro-4'-carboxyacetophenone; 3-Chloro-4-acetylbenzoic Acid; 1-(3-Chloro-4-carboxyphenyl)ethan-1-one; 4-Acetyl-2-chlorobenzoic Acid; 2-Chloro-4-acetylbenzoic Acid; 3-Chloro-4-acetophenonecarboxylic Acid; 4-Acetyl-3-chlorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Carboxy-3-Chloroacetophenone is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. The compound may be moisture-sensitive; ensure containers are sealed after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.