Description

Cyclopentanesulfonic Acid, 2-Amino-, cis- (9Ci) is a specialized chiral sulfonic acid derivative that serves as a high-value building block in advanced organic synthesis. Its unique cis-fused cyclopentane ring system with adjacent amino and sulfonic acid functionalities makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis in enantioselective synthesis.
• Agrochemical Research: Building block for creating new, targeted pesticides and herbicides with specific chiral activity.
• Peptidomimetic Chemistry: Incorporation into peptide backbones to create metabolically stable analogs with modified physicochemical properties.
• Material Science Monomer: Potential monomer for synthesizing specialty polymers with sulfonic acid groups for ion-exchange or conductive applications.
• Chemical Biology Probe Development: Used to create activity-based probes or affinity labels for studying enzyme function.

Basic Information

Product Name	Cyclopentanesulfonic Acid, 2-Amino-, cis- (9Ci)
CAS No.	114850-07-6
Molecular Formula	C5H11NO3S
Molecular Weight	165.21 g/mol
Synonyms	cis-2-Aminocyclopentanesulfonic Acid; (1R,2S)-2-Aminocyclopentanesulfonic Acid; (1S,2R)-2-Aminocyclopentanesulfonic Acid; 2-Amino-cis-cyclopentanesulfonic Acid; ACPSA; cis-ACPS; Cyclopentanesulfonic acid, 2-amino-, (1R,2S)-rel-; (1R,2S)-rel-2-Aminocyclopentanesulfonic acid
EINECS	Contact for details

Quality Control

Our Cyclopentanesulfonic Acid, 2-Amino-, cis- (9Ci) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including chiral purity determination by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect purity and stability. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.