Description

2H-Cyclopenta[B]Furan-2-One, Hexahydro-5-(Phenylmethoxy)-4-[(Phenylmethoxy)Methyl]-, [3As-(3Aa,4A,5B,6Aa)]- is a high-purity, stereochemically defined organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key chiral building block in the development of complex, biologically active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug research.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where the defined spatial orientation of the molecule is crucial for biological activity.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or a model substrate for developing and testing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals requiring precise stereochemical control.
• Academic & Contract Research: A valuable tool for university laboratories and CROs (Contract Research Organizations) engaged in cutting-edge organic chemistry and medicinal chemistry projects.

Basic Information

Item	Details
Product Name	2H-Cyclopenta[B]Furan-2-One, Hexahydro-5-(Phenylmethoxy)-4-[(Phenylmethoxy)Methyl]-, [3As-(3Aa,4A,5B,6Aa)]-
CAS No.	114826-79-8
Molecular Formula	C22H26O5
Molecular Weight	370.44 g/mol
Synonyms	Hexahydro-5-(benzyloxy)-4-[(benzyloxy)methyl]-2H-cyclopenta[b]furan-2-one (3aR,4R,5S,6aR)-Isomer; (3aR,4R,5S,6aR)-Hexahydro-5-(phenylmethoxy)-4-[(phenylmethoxy)methyl]-2H-cyclopenta[b]furan-2-one; [3As-(3Aa,4A,5B,6Aa)]- Hexahydro-5-(benzyloxy)-4-(benzyloxymethyl)-2H-cyclopenta[b]furan-2-one; CAS 114826-79-8; A Chiral Lactone Intermediate; Benzyl-protected Cyclopentane Fused Lactone
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chiral purity. Quality is verified through comprehensive analytical methods including HPLC, chiral GC/HPLC, and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.