Description

tert-Butyl 4'-(Bromomethyl)Biphenyl-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its biphenyl core and reactive bromomethyl functionality. This compound matters as a critical building block in modern organic synthesis, enabling the efficient construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its biphenyl structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and material science.
• Organic Electronics Research: Acts as a monomer or building block in the development of organic semiconductors and light-emitting materials.
• Custom Chemical Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in cross-coupling and functional group transformation reactions.

Basic Information

Product Name	tert-Butyl 4'-(Bromomethyl)Biphenyl-2-Carboxylate
CAS No.	114772-40-6
Molecular Formula	C₁₈H₁₉BrO₂
Molecular Weight	347.25 g/mol
Synonyms	2-Biphenylcarboxylic acid, 4'-(bromomethyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4'-(bromomethyl)[1,1'-biphenyl]-2-carboxylate; tert-Butyl 4'-(bromomethyl)-[1,1'-biphenyl]-2-carboxylate; 4'-(Bromomethyl)biphenyl-2-carboxylic acid tert-butyl ester; Biphenyl-2-carboxylic acid, 4'-(bromomethyl)-, tert-butyl ester; TBBC; CAS 114772-40-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 4'-(Bromomethyl)Biphenyl-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.