Description

(2-Trimethylstannanyl-Phenyl)-Carbamic Acid tert-Butyl Ester is a high-purity organotin intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a versatile building block in the preparation of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring organotin chemistry for carbon-carbon bond formation.
• Stille Cross-Coupling Reactions: Serves as a crucial reagent for the palladium-catalyzed coupling of aryl or vinyl halides with organotin compounds, enabling the construction of complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where specific organometallic intermediates are required.
• Material Science Research: Employed in the development of advanced materials, including polymers and catalysts with tailored properties.
• Organic Synthesis Building Block: Provides a protected aniline functionality with a reactive trimethyltin group, offering versatile handles for further chemical modification.
• Catalyst and Ligand Preparation: Acts as a starting material for the synthesis of specialized organotin catalysts or ligands used in homogeneous catalysis.

Basic Information

Product Name	(2-Trimethylstannanyl-Phenyl)-Carbamic Acid tert-Butyl Ester
CAS No.	114552-32-8
Molecular Formula	C14H23NO2Sn
Molecular Weight	356.04 g/mol
Synonyms	tert-Butyl (2-(trimethylstannyl)phenyl)carbamate; N-(tert-Butoxycarbonyl)-2-(trimethylstannyl)aniline; 2-(Trimethylstannyl)phenylcarbamic Acid tert-Butyl Ester; Boc-2-(Trimethylstannyl)aniline; (2-(Trimethylstannyl)phenyl)carbamic Acid 1,1-Dimethylethyl Ester; Stille Reagent Boc-Protected; N-Boc-2-(Trimethyltin)aniline
EINECS	Contact for details

Quality Control

Our (2-Trimethylstannanyl-Phenyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Tin (Sn) Content	33.0 - 33.5%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.