Description

Milbemycin A3 Oxime is a semi-synthetic derivative of the naturally occurring milbemycin family, a class of 16-membered macrolides. This compound is a crucial intermediate in the synthesis of high-value, potent endectocides used in veterinary and agricultural applications. It is primarily sought by manufacturers in the animal health and crop protection industries for developing advanced parasiticides and acaricides.

Application

• Key Intermediate for Veterinary Parasiticides: Serves as a critical building block in the synthesis of milbemycin-based endectocides for livestock and companion animals.
• Agrochemical Manufacturing: Used in the production of advanced miticides and nematicides for crop protection.
• Research & Development: Employed in pharmaceutical and agrochemical R&D for studying structure-activity relationships and developing new active ingredients.
• Active Pharmaceutical Ingredient (API) Synthesis: A vital precursor in the multi-step synthesis of final API forms for antiparasitic formulations.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory testing in manufacturing.

Basic Information

Product Name	Milbemycin A3 Oxime
CAS No.	114177-14-9
Molecular Formula	C₃₂H₄₅NO₇
Molecular Weight	555.71 g/mol
Synonyms	5-O-Demethyl-28-deoxy-6,28-epoxy-25-(1,3-dimethyl-1-butenyl)-12-fluoro-6,28-seco-milbemycin A4 5-oxime; (5Z,7E)-5-(Hydroxyimino)-6,28-epoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-12-fluoro-3,4,5,6,7,9,10,11,12,13,14,15,16,17,21,22,23,24,25,26-icosahydro-3,14-dihydroxy-4,8,10,12,16,20,22-heptamethyl-18-oxo-9,15:21,23-dimetheno-13,17-methano-2H,8H-pyrano[4,3-g][2]benzoxacyclooctadecine-2-carboxylic Acid Methyl Ester; Milbemycin α3 Oxime; LL-F28249-α Oxime
EINECS	Contact for details

Quality Control

Our Milbemycin A3 Oxime is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.