Description

3-(4-Chloro-2-Fluorophenyl)-1-Methyl-6-(Trifluoromethyl)Pyrimidine-2,4(1H,3H)-Dione is a high-purity, advanced pharmaceutical intermediate with the CAS number 114136-66-2. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a reliable building block for research and commercial-scale production. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides and pesticides due to its fluorinated pyrimidine structure.
• Chemical Synthesis: Serves as a versatile precursor for creating other specialty fluorinated heterocyclic compounds.
• Material Science: Potential application in the research of advanced materials, such as organic electronic components.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-(4-Chloro-2-Fluorophenyl)-1-Methyl-6-(Trifluoromethyl)Pyrimidine-2,4(1H,3H)-Dione
CAS No.	114136-66-2
Molecular Formula	C12H7ClF4N2O2
Molecular Weight	322.64 g/mol
Synonyms	1-Methyl-3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione; 3-(4-Chloro-2-fluorophenyl)-1-methyl-6-(trifluoromethyl)-2,4(1H,3H)-pyrimidinedione; 1-Methyl-3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)uracil; 6-(Trifluoromethyl)-1-methyl-3-(4-chloro-2-fluorophenyl)uracil; 114136-66-2; Fluorinated pyrimidine intermediate; 4-Chloro-2-fluorophenyl uracil derivative
EINECS	Contact for details

Quality Control

Our production of 3-(4-Chloro-2-Fluorophenyl)-1-Methyl-6-(Trifluoromethyl)Pyrimidine-2,4(1H,3H)-Dione adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.