Description

3-Oxetanecarboxylic Acid is a versatile heterocyclic building block featuring a strained oxetane ring fused with a carboxylic acid functional group. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is particularly sought after for the development of novel active ingredients and functional materials. Industries including pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis rely on this high-purity intermediate.

Application

• Pharmaceutical Intermediate: Key synthon for constructing active pharmaceutical ingredients (APIs), especially in medicinal chemistry for probing structure-activity relationships.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organocatalysts for asymmetric synthesis.
• Bioconjugation & Linker Chemistry: Useful for creating cleavable linkers in antibody-drug conjugates (ADCs) and prodrugs.
• Academic & Industrial R&D: A fundamental reagent for exploratory organic synthesis and method development in chemical research.

Basic Information

Product Name	3-Oxetanecarboxylic Acid
CAS No.	114012-41-8
Molecular Formula	C4H6O3
Molecular Weight	102.09 g/mol
Synonyms	Oxetane-3-carboxylic Acid; 3-Carboxyoxetane; Oxetan-3-ylcarboxylic Acid; 3-Oxetane Carboxylic Acid; Oxetane-3-carboxylic acid (9CI); 1,3-Propylene oxide-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Oxetanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.