Description

(1,3-Difluoro-2-Propyl)-p-Toluenesulphonate is a specialized organofluorine building block and sulfonate ester of significant value in advanced organic synthesis. This compound serves as a critical intermediate for introducing the 1,3-difluoro-2-propyl moiety into target molecules, enabling the development of novel materials and active pharmaceutical ingredients (APIs). It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex fluorinated architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel fluorinated pesticides and herbicides, where fluorine atoms can enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Employed in the creation of fluorinated components for advanced display technologies and organic light-emitting diodes.
• Polymer & Material Science: Acts as a monomer or modifier for introducing fluorine into polymers to alter surface properties, chemical resistance, and thermal stability.
• Cross-coupling Reactions: Serves as an electrophilic coupling partner in transition metal-catalyzed reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	(1,3-Difluoro-2-Propyl)-p-Toluenesulphonate
CAS No.	113557-78-1
Molecular Formula	C11H14F2O3S
Molecular Weight	264.29 g/mol
Synonyms	1,3-Difluoro-2-propyl p-toluenesulfonate; p-Toluenesulfonic acid 1,3-difluoro-2-propyl ester; 2-(1,3-Difluoropropyl)-4-methylbenzenesulfonate; 4-Methylbenzenesulfonic acid (1,3-difluoropropan-2-yl) ester; (1,3-Difluoropropan-2-yl) 4-methylbenzenesulfonate; 1,3-Difluoro-2-propyl tosylate; DFPT Tosylate
EINECS	Contact for details

Quality Control

Our (1,3-Difluoro-2-Propyl)-p-Toluenesulphonate is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.