Description

2-Chloro-4-Aminophenylalcohol is a versatile aromatic amine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a hydroxyl group on a chlorinated benzene ring, makes it a valuable intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators, where the chloroaniline moiety provides bioactivity.
• Dye and Pigment Manufacturing: Serves as a diazo component or coupling agent for producing azo dyes and high-performance pigments.
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polyamides, polyurethanes, and epoxy resins, enhancing material properties.
• Liquid Crystal & OLED Materials: A building block for synthesizing advanced organic electronic materials used in displays and lighting.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl structures.
• Corrosion Inhibitor Formulation: Incorporated into formulations that protect metals in industrial processes.
• Research & Development: A valuable reagent for medicinal chemistry and chemical biology research in academic and industrial laboratories.

Basic Information

Product Name	2-Chloro-4-Aminophenylalcohol
CAS No.	113372-69-3
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	2-Chloro-4-hydroxyaniline; 4-Amino-2-chlorophenol; 2-Chloro-4-aminophenol; 4-Amino-2-chlorobenzenol; 2-Chloro-1-hydroxy-4-aminobenzene; 1-Amino-3-chloro-4-hydroxybenzene; 2-Chloro-4-aminophenol; 2-Chloro-4-hydroxybenzenamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Aminophenylalcohol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.