Description

5-Methoxy-3,4-Dihydro-2H-Chromene-3-Carboxylic Acid is a versatile chromene derivative that serves as a key chiral building block and synthetic intermediate in advanced organic synthesis. Its unique fused ring structure and functional groups make it valuable for constructing complex molecules with specific stereochemistry. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Research: Used as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Serves as a building block for creating complex fragrance molecules, dyes, and specialty polymers.
• Academic & R&D: Employed in methodological studies for asymmetric synthesis, cyclization reactions, and catalysis research.
• Material Science: Investigated as a monomer or precursor for advanced polymeric materials with specific optical or electronic properties.

Basic Information

Product Name	5-Methoxy-3,4-Dihydro-2H-Chromene-3-Carboxylic Acid
CAS No.	112904-78-6
Molecular Formula	C12H14O5
Molecular Weight	238.24 g/mol
Synonyms	5-Methoxy-3,4-dihydro-2H-1-benzopyran-3-carboxylic acid; 3-Carboxy-5-methoxy-3,4-dihydro-2H-chromene; 5-Methoxychroman-3-carboxylic acid; 2H-1-Benzopyran-3-carboxylic acid, 5-methoxy-3,4-dihydro-; 5-Methoxy-3,4-dihydro-2H-1-benzopyran-3-carboxylic acid; 5-Methoxy-3,4-dihydrocoumarin-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Methoxy-3,4-Dihydro-2H-Chromene-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.