Description

(R)-(+)-5-(Hydroxymethyl)-2(5H)-Furanone is a high-value chiral lactone building block, essential for the synthesis of complex bioactive molecules. Its enantiomeric purity and functionalized furanone structure make it a critical intermediate for creating optically active pharmaceuticals and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral, anticancer, and other bioactive compounds.
• Agrochemical Synthesis: Used in the research and development of novel, enantiomerically pure pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile building block for fragrances, flavors, and advanced polymeric materials.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems.
• Natural Product Synthesis: A valuable starting material for the total synthesis of complex natural products containing butenolide motifs.

Basic Information

Product Name	(R)-(+)-5-(Hydroxymethyl)-2(5H)-Furanone
CAS No.	112837-17-9
Molecular Formula	C5H6O3
Molecular Weight	114.10 g/mol
Synonyms	(R)-5-(Hydroxymethyl)furan-2(5H)-one; (R)-(+)-5-Hydroxymethyl-2(5H)-furanone; (R)-(-)-5-Hydroxymethylbutenolide; (R)-HMB; (R)-5-Hydroxymethyl-2-buten-4-olide; (3R)-5-(Hydroxymethyl)-2H-furan-2-one; (R)-5-Hydroxymethyl-2(5H)-furanone
EINECS	Contact for details

Quality Control

Our (R)-(+)-5-(Hydroxymethyl)-2(5H)-Furanone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.