Description

1-Methanesulfinyl-4-Methylsulfanyl-6,7-Dihydro-5H-Cyclopenta[D]Pyridazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating sulfinyl and methylsulfanyl functional groups. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the production of proprietary drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially in the development of kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new chemical entities in drug discovery pipelines.
• Process Chemistry & Scale-Up: Used in the optimization and pilot-scale production of APIs, where consistent quality and purity are paramount for regulatory filings.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) supporting global pharmaceutical development.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry, sulfoxide reactivity, and novel synthetic methodologies.

Basic Information

Product Name	1-Methanesulfinyl-4-Methylsulfanyl-6,7-Dihydro-5H-Cyclopenta[D]Pyridazine
CAS No.	112740-87-1
Molecular Formula	C9H12N2OS2
Molecular Weight	228.33 g/mol
Synonyms	1-(Methylsulfinyl)-4-(methylthio)-6,7-dihydro-5H-cyclopenta[d]pyridazine; 4-(Methylthio)-1-(methylsulfinyl)-6,7-dihydro-5H-cyclopenta[d]pyridazine; 6,7-Dihydro-5H-cyclopenta[d]pyridazine, 1-(methylsulfinyl)-4-(methylthio)-; Cyclopenta[d]pyridazine, 6,7-dihydro-5H-, 1-(methylsulfinyl)-4-(methylthio)-; 1-Methanesulfinyl-4-methylsulfanyl-6,7-dihydro-5H-cyclopenta[d]pyridazine
EINECS	Contact for details

Quality Control

Our 1-Methanesulfinyl-4-Methylsulfanyl-6,7-Dihydro-5H-Cyclopenta[D]Pyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting our commitment to supply reliability and regulatory compliance for our global pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.