Description

Methanesulfonic Acid 3-tert-Butoxycarbonylamino-Propyl Ester is a specialized chemical building block designed for advanced organic synthesis. This compound is valued for its role as a protected amino acid derivative, facilitating controlled reactions in complex molecular assembly. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative, enabling the controlled elongation of peptide chains.
• Prodrug Development: Serves as a precursor for designing prodrugs, where the ester linkage can be cleaved under specific physiological conditions.
• Bioconjugation Chemistry: Facilitates the site-specific modification of proteins, antibodies, or other biomolecules for drug delivery and diagnostic applications.
• Fine Chemical Synthesis: Employed in the research and development of complex organic molecules, including catalysts and ligands for asymmetric synthesis.
• Agrochemical Research: Used as an intermediate in the development of new crop protection agents and plant growth regulators.

Basic Information

Product Name	Methanesulfonic Acid 3-tert-Butoxycarbonylamino-Propyl Ester
CAS No.	112663-43-1
Molecular Formula	C10H21NO5S
Molecular Weight	267.34 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]propyl methanesulfonate; Boc-3-aminopropyl methanesulfonate; N-Boc-3-aminopropyl methanesulfonate; 1-[(tert-Butoxycarbonyl)amino]-3-(methylsulfonyloxy)propane; 3-(Boc-amino)propyl methanesulfonate; Methanesulfonic acid, ester with N-(3-hydroxypropyl)carbamic acid tert-butyl ester; Boc-NH-(CH2)3-OSO2CH3
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid 3-tert-Butoxycarbonylamino-Propyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.