Description

3'-Demethylnobiletin is a specific, naturally occurring polymethoxyflavone derivative, a key compound for research and development in the life sciences. Its value lies in its role as a reference standard and active pharmaceutical ingredient (API) intermediate for investigating biological pathways and therapeutic potential. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced chemical synthesis sectors.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of nobiletin and related citrus flavonoids in drug development and quality control.
• Bioactive Compound Research: Serves as a critical tool in preclinical studies to investigate anti-inflammatory, neuroprotective, and anticancer mechanisms of action.
• Nutraceutical Ingredient Development: Employed in the formulation and standardization of high-end dietary supplements targeting cognitive health and metabolic support.
• Chemical Synthesis Intermediate: Acts as a building block for the semi-synthesis of novel flavonoid derivatives with enhanced bioactivity or improved pharmacokinetic properties.
• Academic & Institutional Research: Utilized in university and contract research organization (CRO) labs for fundamental studies on natural product chemistry and pharmacology.

Basic Information

Product Name	3'-Demethylnobiletin
CAS No.	112448-39-2
Molecular Formula	C₂₀H₂₀O₇
Molecular Weight	372.37 g/mol
Synonyms	5,6,7,8,4'-Pentamethoxyflavone; 3'-Desmethylnobiletin; 5,6,7,8,4'-Pentamethoxyflavone; Nobiletin 3'-demethyl derivative; 3'-Hydroxynobiletin methyl ether (ambiguous); Flavone, 5,6,7,8,4'-pentamethoxy-
EINECS	Contact for details

Quality Control

Our 3'-Demethylnobiletin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.