Description

2-Cyclobuten-1-One, 2-Chloro-3-(1,1-Dimethylethyl)- (CAS 112381-38-1) is a specialized chlorinated cyclobutenone derivative that serves as a high-value synthetic intermediate. Its unique sterically hindered structure makes it a critical building block for constructing complex molecular architectures in advanced organic synthesis. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for constructing complex, sterically hindered ketone frameworks.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its chlorinated cyclobutenone core contributes to unique biological activity.
• Organic Synthesis Building Block: A versatile reagent for Diels-Alder reactions and other cycloadditions to create complex polycyclic compounds.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-Cyclobuten-1-One, 2-Chloro-3-(1,1-Dimethylethyl)-
CAS No.	112381-38-1
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	2-Chloro-3-tert-butylcyclobutenone; 2-Chloro-3-(tert-butyl)cyclobut-2-en-1-one; 3-tert-Butyl-2-chlorocyclobutenone; 2-Chloro-3-(1,1-dimethylethyl)-2-cyclobuten-1-one; tert-Butyl 2-chlorocyclobutenone; 2-Chloro-3-tert-butyl-2-cyclobuten-1-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(1,1-Dimethylethyl)-2-cyclobuten-1-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to reliable supply and batch-to-batch consistency supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Handle and store under an inert atmosphere if prolonged storage is required to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.