Description

2-Hexanone, 4-Hydroxy-3-Methyl-, [R-(R*,R*)]- (9Ci) is a chiral, optically active ketone derivative with a defined stereochemistry, making it a valuable building block for asymmetric synthesis. Its specific stereoconfiguration is critical for applications requiring high enantiomeric purity, such as in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research and production in fine chemical, pharmaceutical, and specialty chemical sectors where precise molecular architecture dictates performance.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug molecules, particularly in routes requiring stereoselective ketone chemistry.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Flavor and Fragrance Ingredient: Acts as a precursor for synthesizing specific chiral aroma compounds, contributing to nuanced scent and flavor profiles.
• Asymmetric Catalyst Ligand Development: Provides a scaffold for creating novel chiral ligands used in catalytic asymmetric transformations.
• Advanced Material Research: Investigated as a monomer or modifying agent for polymers with specific optical or structural properties.
• Academic and R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Hexanone, 4-Hydroxy-3-Methyl-, [R-(R*,R*)]- (9Ci)
CAS No.	112294-94-7
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(4R)-4-Hydroxy-3-methylhexan-2-one; (R)-4-Hydroxy-3-methyl-2-hexanone; 4-Hydroxy-3-methyl-2-hexanone, (R)-; 2-Hexanone, 4-hydroxy-3-methyl-, (4R)-; [R-(R*,R*)]-4-Hydroxy-3-methyl-2-hexanone; (4R)-3-Methyl-4-hydroxyhexan-2-one; (R)-3-Methyl-4-hydroxy-2-hexanone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production is supported by advanced analytical techniques including chiral HPLC, GC, and NMR to ensure high enantiomeric excess (ee) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles is provided with each batch, supporting compliance with cGMP and other relevant regulatory frameworks for advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.