Description

2-Hexanone, 4-Hydroxy-3-Methyl-, (3R,4S)- (9Ci) is a chiral, optically active ketone derivative with a defined stereochemistry, making it a valuable building block for asymmetric synthesis. Its precise molecular configuration is critical for applications requiring high enantiomeric purity and specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, particularly for introducing stereocenters.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides where biological activity is stereospecific.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing specific, high-value aroma compounds with defined olfactory characteristics.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in catalytic reactions to study or induce chirality.
• Material Science: Investigated as a monomer or modifying agent for creating polymers with specialized optical or mechanical properties.
• Academic & R&D: A standard for method development in analytical chemistry (e.g., chiral chromatography) and for fundamental studies in organic synthesis.

Basic Information

Product Name	2-Hexanone, 4-Hydroxy-3-Methyl-, (3R,4S)- (9Ci)
CAS No.	112294-91-4
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(3R,4S)-4-Hydroxy-3-methylhexan-2-one; 4-Hydroxy-3-methyl-2-hexanone, (3R,4S)-; (3R,4S)-3-Methyl-4-hydroxy-2-hexanone; 2-Hexanone, 4-hydroxy-3-methyl-, (3R,4S)-; (3R,4S)-4-Hydroxy-3-methyl-2-hexanone; L-threo-4-Hydroxy-3-methylhexan-2-one
EINECS	Contact for details

Quality Control

Our chiral intermediates are produced under strict quality management systems. Each batch is characterized using advanced analytical techniques including Chiral HPLC and NMR to confirm identity, stereochemical purity (enantiomeric excess), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.