Description

Poly(n-Isopropylacrylamide-Co-Butyl Methacrylate) is a synthetic, temperature-responsive copolymer that combines the properties of its constituent monomers. This material is engineered to provide a sharp, reversible phase transition in aqueous solutions, making it a critical component for advanced material design. It is primarily sought by researchers and product developers in the pharmaceutical, biomedical, and specialty coatings industries for creating smart hydrogels, drug delivery systems, and responsive surfaces.

Application

• Drug Delivery Systems: As a key component in temperature-triggered controlled release formulations and injectable depots.
• Biomedical Research: For creating smart cell culture substrates, tissue engineering scaffolds, and bioseparation media.
• Sensor Technology: In the development of optical or mechanical sensors that respond to thermal changes.
• Smart Coatings & Films: Used to fabricate surfaces with switchable wettability or adhesion properties.
• Chromatography & Purification: As a stationary phase in affinity chromatography for biomolecule separation.
• Actuators & Microfluidics: For building micro-valves and pumps that operate based on thermal stimuli.

Basic Information

Product Name	Poly(n-Isopropylacrylamide-Co-Butyl Methacrylate)
CAS No.	111984-73-7
Molecular Formula	(C6H11NO)x(C8H14O2)y
Molecular Weight	Varies by monomer ratio (Contact for details)
Synonyms	PNIPAM-co-BMA; Poly(N-isopropylacrylamide-co-butyl methacrylate); NIPAM-BMA copolymer; Thermoresponsive PNIPAM-BMA copolymer; p(NIPAAm-co-BMA); Poly(NIPAAm-co-BMA); Smart hydrogel copolymer; LCST polymer
EINECS	Contact for details

Quality Control

Our Poly(n-Isopropylacrylamide-Co-Butyl Methacrylate) is produced under a rigorous quality management system. Each batch is characterized to ensure consistent composition, molecular weight, and thermal transition behavior. Certificates of Analysis (COA) detailing monomer ratio, molecular weight distribution, and phase transition temperature are provided and available upon request to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term stability, consider storing under an inert atmosphere or in a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Monomer Ratio (NIPAM:BMA)	As per customer requirement (e.g., 90:10, 80:20)
Number Average Molecular Weight (Mn)	5 kDa - 200 kDa (Customizable)
Polydispersity Index (PDI)	< 1.5 (Typical)
Lower Critical Solution Temperature (LCST)	~32°C (Adjustable based on composition)
Residual Monomer	< 0.5% (by HPLC)
Loss on Drying	< 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.