Description

cis-2-Carbomethoxycyclohexane-1-Carboxylic Acid is a versatile bifunctional cyclohexane derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in the precise spatial arrangement of its ester and carboxylic acid functional groups, enabling stereoselective synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing advanced active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drug candidates, particularly those targeting central nervous system and cardiovascular diseases.
• Asymmetric Synthesis: Chiral building block for constructing complex, stereodefined molecular architectures in medicinal chemistry.
• Ligand and Catalyst Development: Starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.
• Academic and R&D: Valuable reagent for methodological development in organic synthesis and stereochemistry research.

Basic Information

Product Name	cis-2-Carbomethoxycyclohexane-1-Carboxylic Acid
CAS No.	111955-05-6
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	cis-1,2-Cyclohexanedicarboxylic acid 2-methyl ester; cis-2-(Methoxycarbonyl)cyclohexanecarboxylic acid; Methyl cis-1,2-cyclohexanedicarboxylate (specific isomer); cis-Hexahydrophthalic acid monomethyl ester; (1R,2S)-rel-2-(Methoxycarbonyl)cyclohexanecarboxylic acid; (1S,2R)-rel-2-(Methoxycarbonyl)cyclohexanecarboxylic acid; Cyclohexane-1-carboxylic acid, 2-(methoxycarbonyl)-, cis-
EINECS	Contact for details

Quality Control

Our cis-2-Carbomethoxycyclohexane-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.