Description

(S)-(-)-3,3μ-Bis(Triphenylsilyl)-1,1μ-Bi-2-Naphthol CAS NO 111795-33-6 is a high-value, chiral binaphthol derivative where the hydroxyl groups are protected by bulky triphenylsilyl groups. This compound serves as a crucial chiral ligand precursor or auxiliary in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel catalytic processes.

Application

• Asymmetric Catalysis: As a chiral ligand or ligand precursor for transition metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation.
• Pharmaceutical Intermediate Synthesis: For the enantioselective synthesis of active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Chiral Resolution: Employed in the resolution of racemic mixtures to obtain single enantiomers.
• Material Science Research: As a building block for chiral polymers, sensors, or liquid crystals with specific optical properties.
• Agrochemical Development: In the research and synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Process Chemistry: A valuable tool for methodology development and studying stereoselective reaction mechanisms in academic and industrial R&D.

Basic Information

Product Name	(S)-(-)-3,3μ-Bis(Triphenylsilyl)-1,1μ-Bi-2-Naphthol
CAS No.	111795-33-6
Molecular Formula	C58H44O2Si2
Molecular Weight	853.15 g/mol
Synonyms	(S)-(-)-3,3'-Bis(triphenylsilyl)-1,1'-bi-2-naphthol; (S)-3,3'-Bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diol; (S)-BINOL-TPS; (S)-H8-BINOL derivative; (S)-(-)-BINOL silyl ether; Chiral binaphthol silyl ether; Asymmetric ligand precursor; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (S)-(-)-3,3μ-Bis(Triphenylsilyl)-1,1μ-Bi-2-Naphthol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.