Description

Heptakis-(2,3,6-Tri-O-ethyl)-β-cyclodextrin is a chemically modified cyclodextrin derivative, specifically a perethylated β-cyclodextrin. This compound is valued for its enhanced solubility in organic solvents and altered cavity properties compared to its native counterpart, making it a powerful molecular encapsulation agent. It is primarily utilized by researchers and formulators in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring selective complexation, solubility enhancement, and chiral separation.

Application

• Pharmaceutical Research & Development: Used as a chiral selector in capillary electrophoresis and HPLC methods for enantiomeric separation and analysis of drug compounds.
• Drug Solubilization & Formulation: Acts as a solubility and stability enhancer for poorly water-soluble active pharmaceutical ingredients (APIs) through host-guest complexation.
• Chemical Synthesis & Catalysis: Serves as a supramolecular catalyst or a reaction medium modifier in organic synthesis due to its hydrophobic cavity in organic phases.
• Agrochemical Formulations: Employed to improve the solubility, stability, and bioavailability of certain pesticides and herbicides.
• Analytical Chemistry: Functions as a stationary phase modifier or mobile phase additive in chromatographic techniques for complex mixture separation.
• Fragrance & Flavor Stabilization: Used to encapsulate volatile or sensitive aroma compounds, controlling their release and protecting them from degradation.

Basic Information

Product Name	Heptakis-(2,3,6-Tri-O-ethyl)-β-cyclodextrin
CAS No.	111689-01-1
Molecular Formula	C70H126O35
Molecular Weight	1479.73 g/mol
Synonyms	Perethylated β-cyclodextrin; 2,3,6-Tri-O-ethyl-β-cyclodextrin; β-Cyclodextrin, heptakis(2,3,6-tri-O-ethyl)-; E-β-CD; TE-β-CD; Ethylated β-cyclodextrin; Heptakis(2,3,6-tri-O-ethyl)cyclomaltoheptaose; NSC 757680
EINECS	Contact for details

Quality Control

Our Heptakis-(2,3,6-Tri-O-ethyl)-β-cyclodextrin is produced under a strict quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, substitution degree, residual solvents, and related substances. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Degree of Substitution (DS)	~21 (Theoretical)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.