Description

Dihydro-2H-Pyran-4,4(3H)-Dicarbonitrile is a versatile heterocyclic building block featuring a reactive dinitrile-substituted tetrahydropyran core. This compound is valued for its role as a key synthetic intermediate in the preparation of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fused or spiro heterocyclic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive nitrile groups for further functionalization.
• Fine Chemical Building Block: Serves as a versatile starting material for creating specialty chemicals, dyes, and functional materials.
• Ligand and Catalyst Development: The nitrile groups can be transformed into various coordinating functionalities for use in metal-organic frameworks (MOFs) or catalytic complexes.
• Academic and Industrial Research: Employed in medicinal chemistry programs for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Dihydro-2H-Pyran-4,4(3H)-Dicarbonitrile
CAS No.	111511-90-1
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	4,4-Dicyanotetrahydropyran; 3,4-Dihydro-2H-pyran-4,4-dicarbonitrile; Tetrahydropyran-4,4-dicarbonitrile; 4,4-Dicyanotetrahydro-2H-pyran; 4,4-Dicyanotetrahydropyran; 4,4-Dicyano-3,4-dihydro-2H-pyran; 2H-Pyran-4,4(3H)-dicarbonitrile, dihydro-
EINECS	Contact for details

Quality Control

Our Dihydro-2H-Pyran-4,4(3H)-Dicarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The product is hygroscopic (moisture-sensitive); ensure containers are sealed after each use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.