Description

2H-Pyran-6-Carboxylicacid,2-Ethoxy-3,4-Dihydro-4-Methyl-,Methylester,(2R,4R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral building block and intermediate of significant interest in advanced organic synthesis. Its precise stereochemistry and functional groups make it a valuable scaffold for constructing complex molecules with specific three-dimensional architectures. This compound is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for creating stereocenters in complex drug molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry can influence biological activity and environmental profile.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Material Science Research: Potential monomer or precursor for developing novel polymers with specific chiral or functional properties.

Basic Information

Product Name	2H-Pyran-6-Carboxylicacid,2-Ethoxy-3,4-Dihydro-4-Methyl-,Methylester,(2R,4R)-Rel-(9Ci)
CAS No.	111301-68-9
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(2R,4R)-2-Ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester; Methyl (2R,4R)-2-ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylate; rel-(2R,4R)-2-Ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester; 2-Ethoxy-4-methyl-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester, (2R,4R)-rel-; Dihydro-2H-pyran-6-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, and chiral chromatography to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.