Description

2-(Tetrahydro-2H-Pyran-2-Ylmethyl)-1H-Isoindole-1,3(2H)-Dione is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules and fine chemicals, offering a protected amine functionality. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring protected amine groups for selective reactions.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing the phthalimide-protected aminomethyltetrahydropyran moiety into complex molecular architectures.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and other functional organic materials.
• Academic & Industrial R&D: A valuable compound for methodological development and exploratory chemistry in both university and corporate laboratory settings.

Basic Information

Product Name	2-(Tetrahydro-2H-Pyran-2-Ylmethyl)-1H-Isoindole-1,3(2H)-Dione
CAS No.	111293-46-0
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	2-[(Tetrahydro-2H-pyran-2-yl)methyl]-1H-isoindole-1,3(2H)-dione; 2-(THP-O-methyl)phthalimide; N-(Tetrahydro-2H-pyran-2-ylmethyl)phthalimide; 1,3-Dioxo-2-(tetrahydro-2H-pyran-2-ylmethyl)isoindoline; Phthalimide, N-(tetrahydro-2H-pyran-2-ylmethyl)-; 2-(Tetrahydro-2H-pyran-2-ylmethyl)isoindoline-1,3-dione
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-2H-Pyran-2-Ylmethyl)-1H-Isoindole-1,3(2H)-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.