Description

Sodium 4-Ethoxybenzene-1-Sulfinate is a versatile organosulfur compound, specifically the sodium salt of 4-ethoxybenzenesulfinic acid. This chemical is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis, particularly in cross-coupling reactions and as a precursor for sulfone derivatives. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those containing sulfone or sulfoxide moieties with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the sulfinate group can be leveraged to create specific bioactive structures.
• Cross-Coupling Reactions: Serves as a sulfinating agent in palladium-catalyzed cross-coupling reactions (e.g., with aryl halides) to form biaryl sulfones, which are important scaffolds in material and medicinal chemistry.
• Polymer & Material Science: Employed as a monomer or modifier in the development of specialty polymers, coatings, and materials with tailored properties such as enhanced thermal stability or specific solubility.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the 4-ethoxyphenylsulfinyl group into target molecules, enabling the exploration of new chemical space in R&D laboratories.
• Ligand & Catalyst Development: Investigated for use in the preparation of novel ligands and organocatalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	Sodium 4-Ethoxybenzene-1-Sulfinate
CAS No.	111243-34-6
Molecular Formula	C8H9NaO3S
Molecular Weight	208.21 g/mol
Synonyms	Sodium 4-ethoxybenzenesulfinate; 4-Ethoxybenzenesulfinic Acid Sodium Salt; Sodium p-Ethoxybenzenesulfinate; p-Ethoxyphenylsulfinic Acid Sodium Salt; 1-Ethoxy-4-sulfinato-Benzene Sodium Salt; Benzenesulfinic acid, 4-ethoxy-, sodium salt (1:1); 4-Ethoxybenzenesulfinate Sodium
EINECS	Contact for details

Quality Control

Our Sodium 4-Ethoxybenzene-1-Sulfinate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key parameters such as assay, impurity profile, and residual solvents are provided and available upon request. We are committed to meeting the stringent requirements of research and cGMP-grade production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.