Description

D-Arginine, Methyl Ester, Monohydrochloride is a high-purity, non-natural enantiomer of the amino acid arginine, modified as a methyl ester hydrochloride salt. This specific chiral form is a critical building block in peptide synthesis and pharmaceutical research, offering precise control over stereochemistry in drug development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require enantiomerically pure intermediates for advanced therapeutic agents and biochemical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in enzymatic studies, receptor-ligand binding assays, and as a standard for analytical method development.
• Peptide Synthesis: Serves as a protected arginine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Proteomics & Metabolomics: Employed as a labeled or unlabeled internal standard in mass spectrometry and chromatography.
• Neuroscience Research: Investigated for its role in nitric oxide synthase (NOS) pathways and related neurological functions.
• Cosmetic Peptides: A potential raw material for synthesizing bioactive peptides used in advanced skincare formulations.

Basic Information

Item	Details
Product Name	D-Arginine, Methyl Ester, Monohydrochloride
CAS No.	111237-99-1
Molecular Formula	C7H17ClN4O2
Molecular Weight	224.69 g/mol
Synonyms	D-Arginine methyl ester hydrochloride; (R)-Methyl 2-amino-5-guanidinopentanoate hydrochloride; H-D-Arg-OMe·HCl; Methyl (R)-2-amino-5-guanidinovalerate hydrochloride; D-Arg-OMe·HCl; Methyl D-argininate hydrochloride; (2R)-2-Amino-5-(diaminomethylideneamino)pentanoic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our D-Arginine, Methyl Ester, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.