Description

8-Fluoro-4-Chromanone is a fluorinated chromanone derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both a chromanone core and a fluorine substituent, makes it a critical intermediate for developing novel compounds with enhanced biological activity and physical properties. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, particularly for synthesizing potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for developing novel fluorinated organic materials, including liquid crystals and specialty polymers.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for studying biological processes and enzyme mechanisms.
• Flavor & Fragrance Industry: Acts as an intermediate for creating complex, fluorinated aroma chemicals and fragrance molecules.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in fluorination and heterocyclic chemistry.

Basic Information

Product Name	8-Fluoro-4-Chromanone
CAS No.	111141-00-5
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	8-Fluorochroman-4-one; 4-Chromanone, 8-fluoro-; 8-Fluoro-3,4-dihydro-2H-1-benzopyran-4-one; 8-Fluoro-4-chromone; 8-Fluorochromanone; 8-Fluoro-2,3-dihydro-4H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Our 8-Fluoro-4-Chromanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.