Description

trans-2-Carbomethoxycyclopentane-1-Carboxylic Acid is a high-purity, versatile chiral synthon and building block in advanced organic synthesis. This compound is valued for its rigid cyclopentane backbone and dual functional groups, which enable precise stereochemical control in the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a foundational structure for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where stereochemical purity is critical.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process optimization in pilot plants.

Basic Information

Product Name	trans-2-Carbomethoxycyclopentane-1-Carboxylic Acid
CAS No.	111138-44-4
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	trans-1-Carboxy-2-methoxycarbonylcyclopentane; (1R,2S)-rel-2-(Methoxycarbonyl)cyclopentanecarboxylic Acid; Methyl (1R,2S)-rel-1,2-cyclopentanedicarboxylate; Cyclopentane-1,2-dicarboxylic acid, 2-methyl ester; trans-Cyclopentane-1,2-dicarboxylic acid monomethyl ester; 2-Methoxycarbonylcyclopentanecarboxylic acid; (1R,2S)-2-Methoxycarbonylcyclopentane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our trans-2-Carbomethoxycyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.