Description

1-Iodo-2-(Methylsulfonyl)Benzene is a high-value, multi-functional aromatic building block characterized by its distinct iodo and methylsulfonyl substituents. This compound is essential for facilitating advanced cross-coupling reactions and serving as a key precursor in the synthesis of complex organic molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring sulfone or aryl iodide functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfone group can impart specific biological activity.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	1-Iodo-2-(Methylsulfonyl)Benzene
CAS No.	110483-14-2
Molecular Formula	C7H7IO2S
Molecular Weight	282.10 g/mol
Synonyms	2-Iodophenyl Methyl Sulfone; o-Iodophenyl Methyl Sulfone; 1-Iodo-2-(Methanesulfonyl)Benzene; Methyl 2-Iodophenyl Sulfone; (2-Iodophenyl)(methyl)sulfone; Benzene, 1-iodo-2-(methylsulfonyl)-; 2-Methylsulfonyl-1-iodobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Iodo-2-(Methylsulfonyl)Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.