Description

3-(4-Chloro-Phenyl)-4,5-Dihydro-Isoxazole-5-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and advanced materials.
• Ligand and Catalyst Development: The isoxazoline core can be utilized to create novel ligands for asymmetric catalysis and metal complexes.

Basic Information

Product Name	3-(4-Chloro-Phenyl)-4,5-Dihydro-Isoxazole-5-Carboxylic Acid
CAS No.	109888-59-7
Molecular Formula	C10H8ClNO3
Molecular Weight	225.63 g/mol
Synonyms	5-Isoxazolecarboxylic acid, 4,5-dihydro-3-(4-chlorophenyl)-; 3-(p-Chlorophenyl)-4,5-dihydro-5-isoxazolecarboxylic acid; 3-(4-Chlorophenyl)-4,5-dihydroisoxazole-5-carboxylic acid; 4,5-Dihydro-3-(4-chlorophenyl)-5-isoxazolecarboxylic acid; 109888-59-7; 3-(4-Chlorophenyl)-δ²-isoxazoline-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Chloro-Phenyl)-4,5-Dihydro-Isoxazole-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.