Description

Ethanone, 1-(3,4-Dihydro-2H-Pyran-5-Yl)-2,2,2-Trifluoro- (9Ci) is a high-purity fluorinated ketone building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a reactive trifluoroacetyl group with a partially saturated pyran ring, enabling precise chemical modifications. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials, leveraging its reactive ketone functionality for polymerization or cross-linking reactions.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and natural product analogs.
• Fluorine Chemistry Studies: Acts as a model compound in research focused on the reactivity and applications of organofluorine molecules.

Basic Information

Product Name	Ethanone, 1-(3,4-Dihydro-2H-Pyran-5-Yl)-2,2,2-Trifluoro- (9Ci)
CAS No.	109317-74-0
Molecular Formula	C7H7F3O2
Molecular Weight	180.13 g/mol
Synonyms	1-(3,4-Dihydro-2H-pyran-5-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(3,4-dihydro-2H-pyran-5-yl)ethanone; 5-Trifluoroacetyl-3,4-dihydro-2H-pyran; 5-Acetyl-3,4-dihydro-2H-pyran, 5-trifluoroacetyl-; 3,4-Dihydro-2H-pyran-5-yl trifluoromethyl ketone; Trifluoromethyl 3,4-dihydro-2H-pyran-5-yl ketone; 109317-74-0 (CAS)
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3,4-Dihydro-2H-Pyran-5-Yl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive ketone moiety, it should be stored separately from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.