Description

(-)-Ecg-4''-o-Me is a specific methylated derivative of (-)-epicatechin gallate, a compound belonging to the flavonoid family. This modified structure is of significant interest for research into structure-activity relationships and the development of novel bioactive compounds. It serves as a valuable reference standard and building block for pharmaceutical, nutraceutical, and life science research. Target industries include fine chemical synthesis, academic research institutions, and R&D departments focused on natural product chemistry and drug discovery.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents, particularly those targeting oxidative stress and inflammation.
• Nutraceutical Ingredient Research: Serves as a precursor or model compound for developing advanced dietary supplements with enhanced bioavailability or specific activity.
• Life Science Research: Employed in biochemical assays and in vitro studies to investigate the biological effects of flavonoid methylation on antioxidant, anti-inflammatory, or other cellular pathways.
• Analytical Chemistry: Functions as a high-purity certified reference material (CRM) for method development, calibration, and quality control in HPLC, LC-MS, or NMR analysis of complex natural product mixtures.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of more complex flavonoid derivatives for commercial or research purposes.

Basic Information

Item	Details
Product Name	(-)-Ecg-4''-o-Me
CAS No.	108907-44-4
Molecular Formula	C23H18O11
Molecular Weight	470.38 g/mol
Synonyms	(-)-Epicatechin-4''-O-methyl gallate; 4''-O-Methyl-(-)-epicatechin gallate; (-)-Epicatechin 4''-methyl gallate; ECG-4''-O-Me; 4''-O-Methyl ECG; 3-O-Galloyl-(-)-epicatechin 4''-methyl ether; (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl 3,4-dihydroxy-5-methoxybenzoate
EINECS	Contact for details

Quality Control

Our (-)-Ecg-4''-o-Me is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide a Certificate of Analysis (COA) with each shipment, detailing batch-specific results. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, cool place. Due to its sensitivity, prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.